PDBsum entry 5cmm

Transport protein

PDB id: 5cmm

Contents

Protein chain

257 a.a.

Ligands

SYM

Waters ×410

PDB id:

5cmm

Name:

Transport protein

Title:

Crystal structure of the gluk2em lbd dimer assembly complex with 2s, 4r-4-methylglutamate

Structure:

Glutamate receptor ionotropic, kainate 2. Chain: a. Fragment: unp p42260 residues 429-544, unp q13002 residues 667-806. Synonym: gluk2,glutamate receptor 6,glur6,excitatory amino acid receptor 4,eaa4. Engineered: yes. Mutation: yes

Source:

Rattus norvegicus, homo sapiens. Rat, human. Organism_taxid: 10116, 9606. Gene: grik2, glur6, grik2, glur6. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.27Å R-factor: 0.144 R-free: 0.163

Authors:

S.Chittori,M.L.Mayer

Key ref:

J.R.Meyerson et al. (2016). Structural basis of kainate subtype glutamate receptor desensitization. Nature, 537, 567-571. PubMed id: 27580033 DOI: 10.1038/nature19352

Date:

16-Jul-15 Release date: 20-Jul-16

Protein chain

P42260  (GRIK2_RAT) -  Glutamate receptor ionotropic, kainate 2 from Rattus norvegicus

Seq: 908 a.a.

Struc: 257 a.a.*

Protein chain

Q13002  (GRIK2_HUMAN) -  Glutamate receptor ionotropic, kainate 2 from Homo sapiens

Seq: 908 a.a.

Struc: 257 a.a.*

* PDB and UniProt seqs differ at 11 residue positions (black crosses)

DOI no: 10.1038/nature19352

Nature 537:567-571 (2016)

PubMed id: 27580033

Structural basis of kainate subtype glutamate receptor desensitization.

J.R.Meyerson, S.Chittori, A.Merk, P.Rao, T.H.Han, M.Serpe, M.L.Mayer, S.Subramaniam.

ABSTRACT

No abstract given.