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PDBsum entry 5cmk

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protein ligands metals Protein-protein interface(s) links
Transport protein PDB id
5cmk

 

 

 

 

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Contents
Protein chains
251 a.a.
Ligands
GLU
LY5
SO4 ×2
Metals
_CL ×2
_LI ×2
Waters ×533
PDB id:
5cmk
Name: Transport protein
Title: Crystal structure of the gluk2em lbd dimer assembly complex with glutamate and ly466195
Structure: Glutamate receptor ionotropic, kainate 2. Chain: a, b. Fragment: unp residues 429-544, 667-806. Synonym: gluk2,glutamate receptor 6,glur6. Engineered: yes. Mutation: yes
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: grik2, glur6. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
1.80Å     R-factor:   0.165     R-free:   0.187
Authors: S.Chittori,M.L.Mayer
Key ref: J.R.Meyerson et al. (2016). Structural basis of kainate subtype glutamate receptor desensitization. Nature, 537, 567-571. PubMed id: 27580033 DOI: 10.1038/nature19352
Date:
16-Jul-15     Release date:   20-Jul-16    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P42260  (GRIK2_RAT) -  Glutamate receptor ionotropic, kainate 2 from Rattus norvegicus
Seq:
Struc:
 
Seq:
Struc:
908 a.a.
251 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 4 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.?
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

 

 
DOI no: 10.1038/nature19352 Nature 537:567-571 (2016)
PubMed id: 27580033  
 
 
Structural basis of kainate subtype glutamate receptor desensitization.
J.R.Meyerson, S.Chittori, A.Merk, P.Rao, T.H.Han, M.Serpe, M.L.Mayer, S.Subramaniam.
 
  ABSTRACT  
 
No abstract given.

 

 

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