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PDBsum entry 5bt4
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Transcription
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PDB id
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5bt4
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PDB id:
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| Name: |
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Transcription
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Title:
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Crystal structure of brd4 first bromodomain in complex with sgc-cbp30 chemical probe
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Structure:
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Bromodomain-containing protein 4. Chain: a, b, c. Fragment: unp residues 44-168. Synonym: protein hunk1, brd4. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: brd4, hunk1. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: r3.
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Resolution:
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1.50Å
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R-factor:
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0.192
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R-free:
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0.214
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Authors:
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C.Tallant,D.Hay,T.Krojer,G.Nunez-Alonso,S.Picaud,J.A.Newman, O.Fedorov,F.Von Delft,C.H.Arrowsmith,A.M.Edwards,C.Bountra, P.E.Brennan,S.Knapp,Structural Genomics Consortium (Sgc)
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Key ref:
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C.Tallant
et al.
Crystal structure of brd4 first bromodomain in comple a 3,5-Dimethylisoxazol ligand.
To be published,
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Date:
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02-Jun-15
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Release date:
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01-Jul-15
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PROCHECK
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Headers
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References
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O60885
(BRD4_HUMAN) -
Bromodomain-containing protein 4 from Homo sapiens
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Seq:
Struc:
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1362 a.a.
127 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 1 residue position (black
cross)
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Links
