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PDBsum entry 5bpb

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protein ligands Protein-protein interface(s) links
Signaling protein PDB id
5bpb

 

 

 

 

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Contents
Protein chains
119 a.a.
127 a.a.
Ligands
NAG ×4
Waters ×148
PDB id:
5bpb
Name: Signaling protein
Title: Crystal structure of the cysteine-rich domain of human frizzled 4 - crystal form i
Structure: Frizzled-4. Chain: a, b, d, c. Fragment: unp residues 42-179. Synonym: hfz4,fze4. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fzd4. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293t.
Resolution:
2.20Å     R-factor:   0.179     R-free:   0.223
Authors: T.-H.Chang,F.-L.Hsieh,K.Harlos,E.Y.Jones
Key ref: T.-H.Chang et al. Structure and functional properties of norrin mimic w signalling with frizzled4, Lrp5/6, And proteoglycan. To be published, . PubMed id: 26158506
Date:
27-May-15     Release date:   01-Jul-15    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q9ULV1  (FZD4_HUMAN) -  Frizzled-4 from Homo sapiens
Seq:
Struc:
 
Seq:
Struc:
537 a.a.
119 a.a.
Protein chains
Pfam   ArchSchema ?
Q9ULV1  (FZD4_HUMAN) -  Frizzled-4 from Homo sapiens
Seq:
Struc:
 
Seq:
Struc:
537 a.a.
127 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 4 residue positions (black crosses)

 

 

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