PDBsum entry 5b3z

Isomerase,sugar binding protein

PDB id: 5b3z

Contents

Protein chains

402 a.a.

Ligands

GLC-GLC ×4

Waters ×1117

PDB id:

5b3z

Name:

Isomerase,sugar binding protein

Title:

Crystal structure of hpin1 ww domain (5-39) fused with maltose-binding protein

Structure:

Peptidyl-prolyl cis-trans isomerase nima-interacting 1, maltose-binding periplasmic protein. Chain: a, b, c, d. Fragment: unp(q13526) 5-39,unp(p0aex9) residues 27-393. Engineered: yes. Mutation: yes

Source:

Homo sapiens, escherichia coli k-12. Human. Organism_taxid: 9606, 83333. Strain: k-12. Gene: pin1, male. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

2.30Å R-factor: 0.183 R-free: 0.224

Authors:

Y.Hanazono,K.Takeda,K.Miki

Key ref:

Y.Hanazono et al. (2016). Structural studies of the N-terminal fragments of the WW domain: Insights into co-translational folding of a beta-sheet protein. Sci Rep, 6, 34654. PubMed id: 27698466 DOI: 10.1038/srep34654

Date:

17-Mar-16 Release date: 26-Oct-16

Protein chains

P0AEX9  (MALE_ECOLI) -  Maltose/maltodextrin-binding periplasmic protein from Escherichia coli (strain K12)

Seq: 396 a.a.

Struc: 402 a.a.*

Protein chains

Q13526  (PIN1_HUMAN) -  Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 from Homo sapiens

Seq: 163 a.a.

Struc: 402 a.a.*

* PDB and UniProt seqs differ at 142 residue positions (black crosses)

Enzyme reactions

• Enzyme class 1: E.C.?
• Enzyme class 2: E.C.5.2.1.8 - peptidylprolyl isomerase.
• Reaction: [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)

Note, where more than one E.C. class is given (as above), each may correspond to a different protein domain or, in the case of polyprotein precursors, to a different mature protein.

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

Added reference

DOI no: 10.1038/srep34654

Sci Rep 6:34654 (2016)

PubMed id: 27698466

Structural studies of the N-terminal fragments of the WW domain: Insights into co-translational folding of a beta-sheet protein.

Y.Hanazono, K.Takeda, K.Miki.

ABSTRACT

No abstract given.