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UniProt functional annotation for P77499 | ||
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| UniProt code: P77499. |
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| Organism: | |
Escherichia coli (strain K12). |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. |
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| Function: | |
Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake from extracellular iron chelators under iron limitation. {ECO:0000269|PubMed:12554644, ECO:0000269|PubMed:12941942}. |
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| Biophysicochemical properties: | |
Kinetic parameters: KM=0.29 mM for ATP {ECO:0000269|PubMed:12554644}; Vmax=4.45 umol/min/mg enzyme {ECO:0000269|PubMed:12554644}; |
| Subunit: | |
Part of the SufBCD complex that contains SufB, SufC and SufD. Interacts directly with SufB and SufD. {ECO:0000269|PubMed:12554644, ECO:0000269|PubMed:12941942}. |
| Subcellular location: | |
Cytoplasm {ECO:0000269|PubMed:12554644}. |
| Similarity: | |
Belongs to the ABC transporter superfamily. Ycf16 family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.