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UniProt functional annotation for P60866 | ||
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| UniProt code: P60866. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Subunit: | |
Component of the 40S small ribosomal subunit. {ECO:0000250}. |
| Subcellular location: | |
Cytoplasm {ECO:0000250}. |
| Ptm: | |
Monoubiquitinated by ZNF598 when a ribosome has stalled during translation of poly(A) sequences, leading to preclude synthesis of a long poly-lysine tail and initiate the ribosome quality control (RQC) pathway to degrade the potentially detrimental aberrant nascent polypeptide (PubMed:28065601, PubMed:28132843). {ECO:0000269|PubMed:28065601, ECO:0000269|PubMed:28132843}. |
| Ptm: | |
Ufmylated by UFL1. {ECO:0000250|UniProtKB:P60867}. |
| Similarity: | |
Belongs to the universal ribosomal protein uS10 family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.