PDBsum entry 5cw1

Hydrolase

PDB id: 5cw1

Contents

Protein chain

279 a.a.

Ligands

SO4 ×2

PYZ ×3

Metals

IOD ×2

Waters ×397

PDB id:

5cw1

Name:

Hydrolase

Title:

Proteinase k complexed with 4-iodopyrazole

Structure:

Proteinase k. Chain: a. Fragment: unp residues 106-384. Synonym: endopeptidase k,tritirachium alkaline proteinase. Engineered: yes

Source:

Engyodontium album. Organism_taxid: 37998. Gene: prok. Expressed in: engyodontium album. Expression_system_taxid: 37998

Resolution:

1.45Å R-factor: 0.132 R-free: 0.153

Authors:

J.D.Bauman,E.Arnold

Key ref:

J.D.Bauman et al. (2016). Rapid experimental sad phasing and hot spot identific with halogenated fragments. Iucrj, 3, 51.

Date:

27-Jul-15 Release date: 30-Dec-15

Protein chain

P06873  (PRTK_PARAQ) -  Proteinase K from Parengyodontium album

Seq: 384 a.a.

Struc: 279 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.3.4.21.64 - peptidase K.
• Reaction: Hydrolysis of keratin and of other proteins, with subtilisin-like specificity. Hydrolyzes peptides amides.