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UniProt functional annotation for P0AB60 | ||
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| UniProt code: P0AB60. |
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| Organism: | |
Escherichia coli O157:H7. |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. |
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| Function: | |
Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane. {ECO:0000255|HAMAP-Rule:MF_00994}. |
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| Subcellular location: | |
Cell inner membrane {ECO:0000255|HAMAP- Rule:MF_00994}; Single-pass membrane protein {ECO:0000255|HAMAP- Rule:MF_00994}; Cytoplasmic side {ECO:0000255|HAMAP-Rule:MF_00994}. |
| Similarity: | |
Belongs to the LapB family. {ECO:0000255|HAMAP- Rule:MF_00994}. |
Annotations taken from UniProtKB at the EBI.