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UniProt functional annotation for P29536 | ||
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| UniProt code: P29536. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
Mediates nucleation of actin filaments. {ECO:0000269|PubMed:26370058}. |
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| Subcellular location: | |
Cytoplasm, myofibril, sarcomere {ECO:0000269|PubMed:26370058}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:A0A0G2K0D3}. Note=Colocalizes with actin filaments in sarcomeres. {ECO:0000250|UniProtKB:A0A0G2K0D3}. |
| Tissue specificity: | |
Detected in lung vascular smooth muscle (at protein level) (PubMed:27144530). Detected in thyroid and extraocular smooth muscle, but not skeletal muscle (PubMed:2026759). Detected in heart, aorta, skeletal muscle, colon, urinary bladder, uterus, stomach, and small intestine (PubMed:11318603). {ECO:0000269|PubMed:2026759, ECO:0000269|PubMed:27144530}. |
| Similarity: | |
Belongs to the tropomodulin family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.