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UniProt functional annotation for P18573 | ||
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| UniProt code: P18573. |
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| Organism: | |
Triticum aestivum (Wheat). |
| Taxonomy: | |
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade; Pooideae; Triticodae; Triticeae; Triticinae; Triticum. |
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| Function: | |
Gliadin is the major seed storage protein in wheat. {ECO:0000305}. |
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| Tissue specificity: | |
Expressed in endosperm. {ECO:0000269|PubMed:2102865}. |
| Ptm: | |
Substrate of transglutaminase. {ECO:0000305|PubMed:12351792}. |
| Allergen: | |
Causes an allergic reaction in human. Is the cause of the celiac disease, also known as celiac sprue or gluten-sensitive enteropathy. {ECO:0000269|PubMed:12351792}. |
| Miscellaneous: | |
An internal 33-mer peptide seems to be the primary initiator of the inflammatory response to gluten in Celiac Sprue patients. {ECO:0000269|PubMed:12351792}. |
| Miscellaneous: | |
The alpha/beta-gliadins can be divided into 5 homology classes. Sequence divergence between the classes is due to single base substitutions and to duplications or deletions within or near direct repeats. There are more than a 100 copies of the gene for alpha/beta- gliadin per haploid genome. {ECO:0000305}. |
| Similarity: | |
Belongs to the gliadin/glutenin family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.