PDBsum entry 4yu0

Transport protein

PDB id: 4yu0

Contents

Protein chains

259 a.a.

Ligands

GLU ×2

PO4 ×6

PEG ×4

Waters ×822

PDB id:

4yu0

Name:

Transport protein

Title:

Crystal structure of a tetramer of glua2 tr mutant ligand binding domains bound with glutamate at 1.26 angstrom resolution

Structure:

Glutamate receptor 2,glutamate receptor 2. Chain: a, b. Synonym: glur-2,ampa-selective glutamate receptor 2,glur-b,glur-k2, glutamate receptor ionotropic,ampa 2,glua2,glur-2,ampa-selective glutamate receptor 2,glur-b,glur-k2,glutamate receptor ionotropic, ampa 2,glua2. Engineered: yes. Mutation: yes

Source:

Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: gria2, glur2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: origami b.

Resolution:

1.26Å R-factor: 0.131 R-free: 0.157

Authors:

M.Chebli,H.Salazar,J.Baranovic,A.L.Carbone,V.Ghisi,K.Faelber,A.Y.Lau, O.Daumke,A.J.R.Plested

Key ref:

M.Chebli et al. Crystal structure of the tetrameric glua2 ligand-Bind domain in complex with glutamate at 1.26 angstroms resolution. To be published, .

Date:

18-Mar-15 Release date: 13-Jan-16

Protein chains

P19491  (GRIA2_RAT) -  Glutamate receptor 2 from Rattus norvegicus

Seq: 883 a.a.

Struc: 259 a.a.*

* PDB and UniProt seqs differ at 4 residue positions (black crosses)