UniProt functional annotation for Q09176

UniProt code: Q09176.

Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Taxonomy: Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
 
Function: Necessary for the splicing of pre-mRNA. The SF1-U2AF59-U2AF23 complex has a role in the recognition of the branch site (5'-UACUAAC- 3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns. {ECO:0000269|PubMed:12374752}.
 
Subunit: Forms a heterodimer with the U2AF large subunit. Can also form a homodimer. U2AF large subunit (U2AF59), U2AF small subunit (U2AF23) and SF1 (bpb1) interact to form a complex required for complex A formation. Interacts with cwf13. {ECO:0000269|PubMed:11414703, ECO:0000269|PubMed:12374752}.
Subcellular location: Nucleus.

Annotations taken from UniProtKB at the EBI.