PDBsum entry 4y99

Contractile protein

PDB id: 4y99

Contents

Protein chains

155 a.a.

74 a.a.

126 a.a.

Ligands

DMS ×6

Metals

_CA ×3

Waters ×102

PDB id:

4y99

Name:

Contractile protein

Title:

Core domain of human cardiac troponin

Structure:

Troponin c, slow skeletal and cardiac muscles. Chain: a. Synonym: tn-c. Engineered: yes. Mutation: yes. Troponin t, cardiac muscle. Chain: b. Fragment: unp residues 193-298. Synonym: tntc,cardiac muscle troponin t,ctnt.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: tnnc1, tnnc. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: tnnt2. Gene: tnni3, tnnc1.

Resolution:

2.00Å R-factor: 0.232 R-free: 0.259

Authors:

S.Takeda

Key ref:

S.Takeda and s.fujiwara Core domain of human cardiac troponin. To be published, .

Date:

17-Feb-15 Release date: 30-Mar-16

Protein chain

P63316  (TNNC1_HUMAN) -  Troponin C, slow skeletal and cardiac muscles from Homo sapiens

Seq: 161 a.a.

Struc: 155 a.a.*

Protein chain

P45379  (TNNT2_HUMAN) -  Troponin T, cardiac muscle from Homo sapiens

Seq: 298 a.a.

Struc: 74 a.a.*

Protein chain

P19429  (TNNI3_HUMAN) -  Troponin I, cardiac muscle from Homo sapiens

Seq: 210 a.a.

Struc: 126 a.a.*

* PDB and UniProt seqs differ at 6 residue positions (black crosses)