PDBsum entry 4y92

Transferase

PDB id: 4y92

Contents

Protein chain

56 a.a.

Ligands

PGE

SO4

GOL ×4

Waters ×13

PDB id:

4y92

Name:

Transferase

Title:

Crystal structure of the intertwined form of the src tyrosine kinase sh3 domain e97t-q128r mutant

Structure:

Protein-tyrosine kinase. Chain: a. Fragment: sh3 domain, unp residues 85-141. Engineered: yes. Mutation: yes

Source:

Avian sarcoma virus pr2257/16. Organism_taxid: 385048. Gene: src. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Resolution:

2.10Å R-factor: 0.212 R-free: 0.233

Authors:

A.Camara-Artigas,J.Bacarizo

Key ref:

A.Camara-Artigas and j.bacarizo Crystal structure of the intertwined form of the src tyrosine kinase sh3 domain e97t-Q128r mutant. To be published, .

Date:

16-Feb-15 Release date: 02-Mar-16

Protein chain

Q64817  (Q64817_AVIS2) -  non-specific protein-tyrosine kinase from Avian sarcoma virus PR2257/16

Seq: 587 a.a.

Struc: 56 a.a.*

* PDB and UniProt seqs differ at 3 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.2.7.10.2 - non-specific protein-tyrosine kinase.
• Reaction: L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site