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UniProt functional annotation for Q14002 | ||
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| UniProt code: Q14002. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Subunit: | |
Homodimer. {ECO:0000269|PubMed:26323304}. |
| Subcellular location: | |
Cell membrane {ECO:0000305}; Lipid-anchor, GPI- anchor {ECO:0000305}. Apical cell membrane {ECO:0000269|PubMed:10436421}. Note=Localized to the apical glycocalyx surface. {ECO:0000269|PubMed:10436421}. |
| Tissue specificity: | |
Expressed in columnar epithelial cells of the colon (at protein level) (PubMed:10436421). Strongly down-regulated in colonic adenocarcinomas. {ECO:0000269|PubMed:10436421}. |
| Similarity: | |
Belongs to the immunoglobulin superfamily. CEA family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.