PDBsum entry 4y2d

Immune system

PDB id: 4y2d

Contents

Protein chains

249 a.a.

97 a.a.

202 a.a.

239 a.a.

88 a.a.

Ligands

NAG-NAG

NAG ×5

7DW ×2

FUC

PDB id:

4y2d

Name:

Immune system

Title:

Crystal structure of the mcd1d/7dw8-5/inktcr ternary complex

Structure:

Antigen-presenting glycoprotein cd1d1. Chain: a, e. Fragment: ectodomain, unp residues 19-297. Engineered: yes. Beta-2-microglobulin. Chain: b, f. Fragment: unp residues 21-119. Engineered: yes. Chimeric tcr valpha14/jalpha18 chain (mouse variable

Source:

Mus musculus. Mouse. Organism_taxid: 10090. Gene: cd1d1, cd1.1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Gene: b2m. Mus musculus, homo sapiens. Mouse, human.

Resolution:

3.05Å R-factor: 0.218 R-free: 0.257

Authors:

D.M.Zajonc,E.D.Yu

Key ref:

A.Birkholz et al. Structural modifications of alphagalcer in both lipid carbohydrate moiety influence activation of murine an inkt cells. To be published, .

Date:

09-Feb-15 Release date: 27-May-15

Protein chains

P11609  (CD1D1_MOUSE) -  Antigen-presenting glycoprotein CD1d1 from Mus musculus

Seq: 336 a.a.

Struc: 249 a.a.

Protein chain

P01887  (B2MG_MOUSE) -  Beta-2-microglobulin from Mus musculus

Seq: 119 a.a.

Struc: 97 a.a.

Protein chains

A0A0B4J1J9  (A0A0B4J1J9_MOUSE) -  T cell receptor alpha variable 11 (Fragment) from Mus musculus

Seq: 114 a.a.

Struc: 202 a.a.

Protein chains

P01848  (TCA_HUMAN) -  T cell receptor alpha chain constant from Homo sapiens

Seq: 140 a.a.

Struc: 202 a.a.*

Protein chains

A0A5B9  (TRBC2_HUMAN) -  T cell receptor beta constant 2 from Homo sapiens

Seq: 178 a.a.

Struc: 239 a.a.*

Protein chains

A2NTY6  (A2NTY6_MOUSE) -  Beta-chain (Fragment) from Mus musculus

Seq: 144 a.a.

Struc: 239 a.a.*

Protein chain

P01887  (B2MG_MOUSE) -  Beta-2-microglobulin from Mus musculus

Seq: 119 a.a.

Struc: 88 a.a.

* PDB and UniProt seqs differ at 11 residue positions (black crosses)