PDBsum entry 4y03

Cell cycle

PDB id: 4y03

Contents

Protein chains

115 a.a.

Ligands

SAL ×2

CIT

Waters ×103

PDB id:

4y03

Name:

Cell cycle

Title:

Crystal structure of the fifth bromodomain of human pb1 in complex with salicylic acid

Structure:

Protein polybromo-1. Chain: a, b. Fragment: unp residues 645-766. Synonym: hpb1,brg1-associated factor 180,baf180,polybromo-1d. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: pbrm1, baf180, pb1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Expression_system_variant: r3.

Resolution:

1.94Å R-factor: 0.234 R-free: 0.281

Authors:

P.Filippakopoulos,S.Picaud,I.Felletar,O.Fedorov,F.Von Delft, A.M.Edwards,C.H.Arrowsmith,C.Bountra,S.Knapp,Structural Genomics Consortium (Sgc)

Key ref:

P.Filippakopoulos et al. Crystal structure of the fifth bromodomain of human p complex with salicylic acid. To be published, .

Date:

05-Feb-15 Release date: 20-May-15

Protein chains

Q86U86  (PB1_HUMAN) -  Protein polybromo-1 from Homo sapiens

Seq: 1689 a.a.

Struc: 115 a.a.

Enzyme reactions

• Enzyme class: E.C.?