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UniProt functional annotation for O16810 | ||
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| UniProt code: O16810. |
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| Organism: | |
Drosophila melanogaster (Fruit fly). |
| Taxonomy: | |
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora. |
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| Function: | |
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. {ECO:0000269|PubMed:9363940}. |
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| Subunit: | |
ORC is composed of six subunits. {ECO:0000250}. |
| Subcellular location: | |
Nucleus {ECO:0000250}. |
| Similarity: | |
Belongs to the ORC1 family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.