|
|
||
|
|
|
|
|
UniProt functional annotation for O67077 | ||
|
|
|
|
|
|
||
| UniProt code: O67077. |
|
||
| Organism: | |
Aquifex aeolicus (strain VF5). |
| Taxonomy: | |
Bacteria; Aquificae; Aquificales; Aquificaceae; Aquifex. |
|
||
|
||
| Function: | |
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins. {ECO:0000255|HAMAP- Rule:MF_01458}. |
|
||
| Cofactor: | |
Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000305|PubMed:16762831}; Note=Binds 1 zinc ion per subunit. {ECO:0000305|PubMed:16762831}; |
| Subunit: | |
The isolated protease domain (residues 405-634) forms a stable hexamer. {ECO:0000269|PubMed:16762831}. |
| Subcellular location: | |
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. |
| Similarity: | |
In the central section; belongs to the AAA ATPase family. {ECO:0000255|HAMAP-Rule:MF_01458}. |
| Similarity: | |
In the C-terminal section; belongs to the peptidase M41 family. {ECO:0000255|HAMAP-Rule:MF_01458}. |
Annotations taken from UniProtKB at the EBI.