 |
PDBsum entry 4whw
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Transcription/transcription inhibitor
|
PDB id
|
|
|
|
4whw
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PDB id:
|
|
|
|
| Name: |
|
Transcription/transcription inhibitor
|
|
|
Title:
|
|
Direct photocapture of bromodomains using tropolone chemical probes
|
|
Structure:
|
|
Bromodomain-containing protein 4. Chain: a. Fragment: unp residues 44-168. Synonym: protein hunk1. Engineered: yes
|
|
Source:
|
|
Homo sapiens. Human. Organism_taxid: 9606. Gene: brd4, hunk1. Expressed in: escherichia coli. Expression_system_taxid: 562
|
|
Resolution:
|
|
|
1.35Å
|
R-factor:
|
0.181
|
R-free:
|
0.201
|
|
|
Authors:
|
|
E.C.Hett,E.L.Piatnitski Chekler,A.Basak,P.D.Bonin,R.A.Denny, A.C.Flick,K.F.Geoghegan,S.Liu,M.T.Pletcher,R.P.Robinson, P.Sahasrabudhe,S.Salter,I.A.Stock,L.H.Jones
|
|
Key ref:
|
|
E.C.Hett
et al.
Direct photocapture of bromodomains using tropolone c probes.
To be published,
.
|
|
|
Date:
|
|
|
23-Sep-14
|
Release date:
|
28-Oct-15
|
|
|
|
|
|
|
PROCHECK
|
|
|
|
|
|
Headers
|
|
|
|
References
|
|
|
|
|
|
|
|
O60885
(BRD4_HUMAN) -
Bromodomain-containing protein 4 from Homo sapiens
|
|
|
|
Seq:
Struc:
|
|
|
|
1362 a.a.
124 a.a.*
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Key: |
 |
PfamA domain |
|
|
 |
Secondary structure |
|
 |
CATH domain |
|
|
*
PDB and UniProt seqs differ
at 1 residue position (black
cross)
|
|
|
|
|
|
|
Links
