 |
PDBsum entry 4wg4
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Transferase/transferase inhibitor
|
PDB id
|
|
|
|
4wg4
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
References listed in PDB file
|
|
|
Key reference
|
|
|
Title
|
|
Calcium-Dependent protein kinase 1 from toxoplasma go (tgcdpk1) in complex with inhibitor uw1613
|
|
|
Author
|
|
E.A.Merritt.
|
|
|
Ref.
|
|
TO BE PUBLISHED ...
|
|
|
|
Secondary reference #1
|
|
|
Title
|
|
Potent and selective inhibitors of cdpk1 from t. Gondii and c. Parvum based on a 5-Aminopyrazole-4-Carboxamide scaffold.
|
|
|
Authors
|
|
Z.Zhang,
K.K.Ojo,
R.Vidadala,
W.Huang,
J.A.Geiger,
S.Scheele,
R.Choi,
M.C.Reid,
K.R.Keyloun,
K.Rivas,
L.K.Siddaramaiah,
K.M.Comess,
K.P.Robinson,
P.J.Merta,
L.Kifle,
W.G.Hol,
M.Parsons,
E.A.Merritt,
D.J.Maly,
C.L.Verlinde,
W.C.Van voorhis,
E.Fan.
|
|
|
Ref.
|
|
Acs Med Chem Lett, 2014,
5,
40-44.
[DOI no: ]
|
|
|
PubMed id
|
|
|
|
|
|
|
|
|
Secondary reference #2
|
|
|
Title
|
|
Toxoplasma gondii calcium-Dependent protein kinase 1 is a target for selective kinase inhibitors.
|
|
|
Authors
|
|
K.K.Ojo,
E.T.Larson,
K.R.Keyloun,
L.J.Castaneda,
A.E.Derocher,
K.K.Inampudi,
J.E.Kim,
T.L.Arakaki,
R.C.Murphy,
L.Zhang,
A.J.Napuli,
D.J.Maly,
C.L.Verlinde,
F.S.Buckner,
M.Parsons,
W.G.Hol,
E.A.Merritt,
W.C.Van voorhis.
|
|
|
Ref.
|
|
Nat Struct Biol, 2010,
17,
602-607.
|
|
|
PubMed id
|
|
|
|
|
|
|
|
|
Secondary reference #3
|
|
|
Title
|
|
Multiple determinants for selective inhibition of apicomplexan calcium-Dependent protein kinase cdpk1.
|
|
|
Authors
|
|
E.T.Larson,
K.K.Ojo,
R.C.Murphy,
S.M.Johnson,
Z.Zhang,
J.E.Kim,
D.J.Leibly,
A.M.Fox,
M.C.Reid,
E.J.Dale,
B.G.Perera,
J.Kim,
S.N.Hewitt,
W.G.Hol,
C.L.Verlinde,
E.Fan,
W.C.Van voorhis,
D.J.Maly,
E.A.Merritt.
|
|
|
Ref.
|
|
J Med Chem, 2012,
55,
2803-2810.
|
|
|
PubMed id
|
|
|
|
|
|
|
|
|
|
|
|
|
