UniProt functional annotation for P33201

UniProt code: P33201.

Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Taxonomy: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
 
Function: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. {ECO:0000269|PubMed:10471698, ECO:0000269|PubMed:19346338, ECO:0000269|PubMed:19789271, ECO:0000269|PubMed:19797078}.
 
Subunit: Associates with the pre-60S ribosomal particle. {ECO:0000269|PubMed:11583614, ECO:0000269|PubMed:19346338, ECO:0000269|PubMed:19789271, ECO:0000269|PubMed:19797078}.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:11583614, ECO:0000269|PubMed:19789271}. Cytoplasm {ECO:0000269|PubMed:19789271}. Note=Shuttles between the nucleus and the cytoplasm. {ECO:0000269|PubMed:19789271}.
Miscellaneous: Present with 18200 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Similarity: Belongs to the universal ribosomal protein uL10 family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.