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UniProt functional annotation for Q8WXH4 | ||
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| UniProt code: Q8WXH4. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. {ECO:0000250}. |
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| Pathway: | |
Protein modification; protein ubiquitination. |
| Domain: | |
The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin-protein ligase complexes. {ECO:0000250}. |
| Similarity: | |
Belongs to the ankyrin SOCS box (ASB) family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.