UniProt functional annotation for P31473

UniProt code: P31473.

Organism: Escherichia coli (strain K12).
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia.
 
Function: Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone.
 
Activity regulation: The complex formed with CadA represents a possible means of regulating RavA activity in response to acid stress conditions. This interaction results in an increase in RavA ATPase activity.
Biophysicochemical properties: Kinetic parameters: KM=790 uM for ATP (at pH 7.5); Note=RavA also has GTPase activity.; pH dependence: Optimum pH is 7.5.;
Subunit: Hexameric oligomer. Interactions of five RavA oligomers with two CadA decamers. Possible formation of a ternary complex RavA-ViaA- CadA. {ECO:0000269|PubMed:16301313}.
Subcellular location: Cytoplasm.
Induction: Expression is sigma S-dependent.
Similarity: Belongs to the RavA family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.