PDBsum entry 4upb

Lyase/hydrolase

PDB id: 4upb

Contents

Protein chains

710 a.a.*

453 a.a.*

* C-alpha coords only

PDB id:

4upb

Name:

Lyase/hydrolase

Title:

Electron cryo-microscopy of the complex formed between the hexameric atpase rava and the decameric inducible decarboxylase ldci

Structure:

Lysine decarboxylase, inducible. Chain: a, b. Synonym: ldc. Engineered: yes. Atpase rava. Chain: c, d, e. Synonym: regulatory atpase variant a. Engineered: yes

Source:

Escherichia coli k-12. Organism_taxid: 83333. Variant: mg1655. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 469008. Expression_system_variant: gold plyss.

Authors:

H.Malet,K.Liu,M.El Bakkouri,S.W.S.Chan,G.Effantin,M.Bacia,W.A.Houry, I.Gutsche

Key ref:

H.Malet et al. (2014). Assembly principles of a unique cage formed by hexameric and decameric E. coli proteins. Elife, 3, e03653. PubMed id: 25097238 DOI: 10.7554/eLife.03653

Date:

15-Jun-14 Release date: 20-Aug-14

Protein chains

P0A9H3  (LDCI_ECOLI) -  Inducible lysine decarboxylase from Escherichia coli (strain K12)

Seq: 715 a.a.

Struc: 710 a.a.

Protein chains

P31473  (RAVA_ECOLI) -  ATPase RavA from Escherichia coli (strain K12)

Seq: 498 a.a.

Struc: 453 a.a.

Enzyme reactions

• Enzyme class 1: Chains A, B: E.C.4.1.1.18 - lysine decarboxylase.
• Reaction: L-lysine + H⁺ = cadaverine + CO2
• Cofactor: Pyridoxal 5'-phosphate
• Enzyme class 2: Chains C, D, E: E.C.3.6.3.- - ?????

Note, where more than one E.C. class is given (as above), each may correspond to a different protein domain or, in the case of polyprotein precursors, to a different mature protein.

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

reference

DOI no: 10.7554/eLife.03653

Elife 3:e03653 (2014)

PubMed id: 25097238

Assembly principles of a unique cage formed by hexameric and decameric E. coli proteins.

H.Malet, K.Liu, M.El Bakkouri, S.W.Chan, G.Effantin, M.Bacia, W.A.Houry, I.Gutsche.

ABSTRACT

No abstract given.