PDBsum entry 4u8v

Transport protein

PDB id: 4u8v

Contents

Protein chains

1044 a.a.

156 a.a.

Ligands

LMT ×5

MIY

Waters ×1343

PDB id:

4u8v

Name:

Transport protein

Title:

Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump acrb

Structure:

Multidrug efflux pump subunit acrb. Chain: a, b, c. Synonym: acrab-tolc multidrug efflux pump subunit acrb,acridine resistance protein b. Engineered: yes. Mutation: yes. Darpin. Chain: d, e. Engineered: yes

Source:

Escherichia coli. Organism_taxid: 562. Gene: acrb, acre, b0462, jw0451. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic construct. Organism_taxid: 32630. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

2.30Å R-factor: 0.193 R-free: 0.238

Authors:

K.M.Pos

Key ref:

T.Eicher et al. (2014). Coupling of remote alternating-Access transport mecha for protons and substrates in the multidrug efflux pu acrb.. Elife, 3, . PubMed id: 25248080

Date:

04-Aug-14 Release date: 15-Oct-14

Protein chains

P31224  (ACRB_ECOLI) -  Multidrug efflux pump subunit AcrB from Escherichia coli (strain K12)

Seq: 1049 a.a.

Struc: 1044 a.a.*

Protein chains

No UniProt id for this chain

Struc: 156 a.a.

* PDB and UniProt seqs differ at 1 residue position (black cross)