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UniProt functional annotation for P15424 | ||
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| UniProt code: P15424. |
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| Organism: | |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. |
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| Function: | |
ATP-dependent RNA helicase required for mitochondrial splicing of group I and II introns. Specifically involved in the ATP- dependent splicing of the bl1 intron of COB. Also required for efficient mitochondrial translation. {ECO:0000269|PubMed:12402239, ECO:0000269|PubMed:15618406, ECO:0000269|PubMed:2535893, ECO:0000269|PubMed:7567443}. |
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| Catalytic activity: | |
Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13; |
| Subcellular location: | |
Mitochondrion matrix {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:14576278}. |
| Domain: | |
The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis. |
| Miscellaneous: | |
Present with 10300 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}. |
| Similarity: | |
Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.