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PDBsum entry 4tvr
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PDB id:
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Ligase
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Title:
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Tandem tudor and phd domains of uhrf2
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Structure:
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E3 ubiquitin-protein ligase uhrf2. Chain: a. Fragment: tandem tudor and phd domains, unp residues 109-395. Synonym: np95/icbp90-like ring finger protein,np95-like ring finger protein,nuclear protein 97,nuclear zinc finger protein np97,ring finger protein 107,ubiquitin-like phd and ring finger domain- containing protein 2,ubiquitin-like-containing phd and ring finger domains protein 2. Engineered: yes.
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf2, nirf, rnf107. Expressed in: escherichia coli. Expression_system_taxid: 469008.
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Resolution:
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2.29Å
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R-factor:
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0.231
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R-free:
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0.260
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Authors:
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J.R.Walker,A.Dong,Q.Zhang,M.Ong,S.Duan,Y.Li,C.Bountra,J.Weigelt, A.M.Edwards,C.H.Arrowsmith,Y.Tong,Structural Genomics Consortium (Sgc)
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Key ref:
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J.R.Walker
et al.
Structure of the tandem tudor and phd domains of uhrf.
To be published,
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Date:
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27-Jun-14
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Release date:
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24-Jun-15
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PROCHECK
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Headers
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References
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Q96PU4
(UHRF2_HUMAN) -
E3 ubiquitin-protein ligase UHRF2 from Homo sapiens
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Seq:
Struc:
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802 a.a.
222 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.2.3.2.27
- RING-type E3 ubiquitin transferase.
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Reaction:
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S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N6- ubiquitinyl-[acceptor protein]-L-lysine
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Links
