 |
PDBsum entry 4rz7
|
|
|
|
PDB id:
|
 |
|
 |
| Name: |
 |
Transferase
|
 |
|
Title:
|
 |
Crystal structure of pvx_084705 with bound pci32765
|
|
Structure:
|
 |
Cgmp-dependent protein kinase, putative. Chain: a. Engineered: yes
|
|
Source:
|
 |
Plasmodium vivax sal-1. Organism_taxid: 126793. Strain: salvador i. Gene: pvx_084705. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.
|
|
Resolution:
|
 |
|
2.35Å
|
R-factor:
|
0.196
|
R-free:
|
0.238
|
|
|
Authors:
|
 |
D.Q.Jiang,W.Tempel,P.Loppnau,S.Graslund,H.He,A.Seitova, C.H.Arrowsmith,A.M.Edwards,C.Bountra,R.Hui,A.Hutchinson,M.El Bakkouri,M.Amani,Structural Genomics Consortium (Sgc)
|
|
Key ref:
|
 |
D.Q.Jiang
et al.
Crystal structure of pvx_084705 with bound pci32765.
To be published,
.
|
 |
|
Date:
|
 |
|
18-Dec-14
|
Release date:
|
14-Jan-15
|
|
|
|
|
|
PROCHECK
|
|
|
|
|
Headers
|
 |
|
|
References
|
|
|
|
|
|
|
A5K0N4
(A5K0N4_PLAVS) -
cGMP-dependent protein kinase from Plasmodium vivax (strain Salvador I)
|
|
|
|
Seq: Struc:
|
 |
 |
 |
846 a.a.
801 a.a.
|
|
|
|
|
|
|
|
|
 |
 |
|
|
Key: |
 |
PfamA domain |
 |
 |
 |
Secondary structure |
 |
|
|
|
|
 |
|
|
 |
 |
 |
 |
Enzyme class:
|
 |
E.C.2.7.11.12
- cGMP-dependent protein kinase.
|
|
 |
 |
 |
 |
 |
Reaction:
|
 |
|
1.
|
L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H+
|
|
2.
|
L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H+
|
|
 |
 |
 |
 |
 |
L-seryl-[protein]
|
+
|
ATP
|
=
|
O-phospho-L-seryl-[protein]
|
+
|
ADP
|
+
|
H(+)
|
|
 |
 |
 |
 |
 |
L-threonyl-[protein]
|
+
|
ATP
|
=
|
O-phospho-L-threonyl-[protein]
|
+
|
ADP
|
+
|
H(+)
|
|
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
|
Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
|
|
 |
');
}
}
 |