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PDBsum entry 4rsv
Go to PDB code:
Structural protein
PDB id
4rsv
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Contents
Protein chain
90 a.a.
Waters
×1
PDB id:
4rsv
Links
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CATH
SCOP
PDBSWS
PDBePISA
ProSAT
Name:
Structural protein
Title:
Human obscurin ig58 domain
Structure:
Obscurin. Chain: a. Fragment: unp residues 4337-4429. Synonym: obscurin-rhogef, obscurin-myosin light chain kinase, obscurin-mlck. Engineered: yes
Source:
Homo sapiens. Human. Organism_taxid: 9606. Gene: obscn, kiaa1556, kiaa1639. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Resolution:
2.41Å
R-factor:
0.260
R-free:
0.280
Authors:
N.T.Wright,M.C.Oehler,C.E.Berndsen,K.E.Du Pont
Key ref:
L.Y.R.Hu et al. Arrhythmia and deregulated ca2+ cycling underlie the development of hypertrophic cardiomyopathy due to mut giant obscurin.
To be published
, .
Date:
11-Nov-14
Release date:
24-Feb-16
PROCHECK
Headers
References
Protein chain
Q5VST9
(OBSCN_HUMAN) - Obscurin from Homo sapiens
Seq:
Struc:
Seq:
Struc:
Seq:
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Struc:
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Seq:
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Seq:
Struc:
Seq:
Struc:
7968 a.a.
90 a.a.
*
Key:
Secondary structure
CATH domain
*
PDB and UniProt seqs differ at 1 residue position (black cross)
Enzyme reactions
Enzyme class:
E.C.2.7.11.1
- non-specific serine/threonine protein kinase.
[IntEnz]
[ExPASy]
[KEGG]
[BRENDA]
Reaction:
1.
L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H
+
2.
L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H
+
L-seryl-[protein]
+
ATP
=
O-phospho-L-seryl-[protein]
+
ADP
+
H(+)
L-threonyl-[protein]
+
ATP
=
O-phospho-L-threonyl-[protein]
+
ADP
+
H(+)
Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
Links
