PDBsum entry 4rly

Structural protein

PDB id: 4rly

Contents

Protein chain

308 a.a.

Ligands

SO4 ×7

Waters ×74

PDB id:

4rly

Name:

Structural protein

Title:

Crystal structure of ankb ankyrin repeats (r1-r9) in complex with nav1.2 ankyrin binding domain

Structure:

Nav1.2 - ankb chimera. Chain: a. Engineered: yes

Source:

Mus musculus, homo sapiens. Mouse, human. Organism_taxid: 10090, 9606. Gene: ank2, scn2a, scn2a1. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

2.50Å R-factor: 0.190 R-free: 0.238

Authors:

Z.Wei,C.Wang,M.Zhang

Key ref:

C.Wang et al. (2014). Structural basis of diverse membrane target recogniti ankyrins.. Elife, 3, . PubMed id: 25383926

Date:

18-Oct-14 Release date: 26-Nov-14

Protein chain

Q01484  (ANK2_HUMAN) -  Ankyrin-2 from Homo sapiens

Seq: 3957 a.a.

Struc: 308 a.a.*

Protein chain

Q99250  (SCN2A_HUMAN) -  Sodium channel protein type 2 subunit alpha from Homo sapiens

Seq: 2005 a.a.

Struc: 308 a.a.*

* PDB and UniProt seqs differ at 291 residue positions (black crosses)