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PDBsum entry 4r8h

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protein ligands Protein-protein interface(s) links
Transcription PDB id
4r8h

 

 

 

 

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JSmol PyMol  
Contents
Protein chains
200 a.a.
Ligands
SP1 ×4
GOL ×7
Waters ×255
PDB id:
4r8h
Name: Transcription
Title: The role of protein-ligand contacts in allosteric regulation of the escherichia coli catabolite activator protein
Structure: Camp-activated global transcriptional regulator crp. Chain: a, b. Synonym: catabolite activator protein, cap, catabolite gene activator, camp receptor protein, crp, camp regulatory protein. Engineered: yes
Source: Escherichia coli. Organism_taxid: 83333. Strain: k12. Gene: crp, cap, csm, b3357, jw5702. Expressed in: escherichia coli. Expression_system_taxid: 562.
Resolution:
1.46Å     R-factor:   0.189     R-free:   0.215
Authors: P.D.Townsend,E.Pohl,T.C.B.Mcleish,T.L.Rodgers,L.C.Glover, H.J.Korhonen,M.R.Wilson,D.R.W.Hodgson,M.J.Cann
Key ref: P.D.Townsend et al. (2015). The Role of Protein-Ligand Contacts in Allosteric Regulation of the Escherichia coli Catabolite Activator Protein. J Biol Chem, 290, 22225-22235. PubMed id: 26187469 DOI: 10.1074/jbc.M115.669267
Date:
02-Sep-14     Release date:   22-Jul-15    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P0ACJ8  (CRP_ECOLI) -  DNA-binding transcriptional dual regulator CRP from Escherichia coli (strain K12)
Seq:
Struc:
210 a.a.
200 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.?
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

 

 
DOI no: 10.1074/jbc.M115.669267 J Biol Chem 290:22225-22235 (2015)
PubMed id: 26187469  
 
 
The Role of Protein-Ligand Contacts in Allosteric Regulation of the Escherichia coli Catabolite Activator Protein.
P.D.Townsend, T.L.Rodgers, L.C.Glover, H.J.Korhonen, S.A.Richards, L.J.Colwell, E.Pohl, M.R.Wilson, D.R.Hodgson, T.C.McLeish, M.J.Cann.
 
  ABSTRACT  
 
No abstract given.

 

 

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