PDBsum entry 4r6a

RNA binding protein

PDB id: 4r6a

Contents

Protein chains

746 a.a.

Ligands

NAG-NAG-BMA-MAN ×2

NAG-NAG-BMA ×4

NAG ×10

HB2 ×2

Waters ×402

PDB id:

4r6a

Name:

RNA binding protein

Title:

Crystal structure of human tlr8 in complex with hybrid-2

Structure:

Toll-like receptor 8. Chain: a, b. Fragment: unp residues 27-827. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: tlr8, unq249/pro286. Expressed in: drosophila melanogaster. Expression_system_taxid: 7227. Expression_system_cell: s2 cell

Resolution:

2.10Å R-factor: 0.204 R-free: 0.259

Authors:

H.Tanji,U.Ohto,T.Shimizu

Key ref:

L.Ganapathi et al. Hybrid-2: animidazoquinoline dual toll-Like receptor agonist that potently activates cytokine production b newborn and adult leukocytes. To be published, .

Date:

22-Aug-14 Release date: 26-Aug-15

Protein chains

Q9NR97  (TLR8_HUMAN) -  Toll-like receptor 8 from Homo sapiens

Seq: 1041 a.a.

Struc: 746 a.a.