PDBsum entry 4qsp

Signaling protein

PDB id: 4qsp

Contents

Protein chain

130 a.a.

Ligands

ALY

SO4 ×2

EDO ×9

Waters ×279

PDB id:

4qsp

Name:

Signaling protein

Title:

Structure of the bromodomain of human atpase family aaa domain- containing protein 2 (atad2) in complex with acetyl-lysine

Structure:

Atpase family aaa domain-containing protein 2. Chain: a. Fragment: bromodomain (residues 981-1108). Synonym: aaa nuclear coregulator cancer-associated protein, ancca. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: atad2, l16, pro2000. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.60Å R-factor: 0.167 R-free: 0.194

Authors:

A.Chaikuad,I.Felletar,F.Von Delft,C.H.Arrowsmith,A.M.Edwards, C.Bountra,S.Knapp,Structural Genomics Consortium (Sgc)

Key ref:

A.Chaikuad et al. Structure of the bromodomain of human atpase family a domain-Containing protein 2 (atad2) in complex with acetyl-Lysine. To be published, .

Date:

06-Jul-14 Release date: 23-Jul-14

Protein chain

Q6PL18  (ATAD2_HUMAN) -  ATPase family AAA domain-containing protein 2 from Homo sapiens

Seq: 1390 a.a.

Struc: 130 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.3.6.1.- - ?????