PDBsum entry 4qqi

Structural protein

PDB id: 4qqi

Contents

Protein chains

176 a.a.

16 a.a.

Ligands

SO4 ×4

UNX ×11

UNL

Waters ×82

PDB id:

4qqi

Name:

Structural protein

Title:

Crystal structure of ankra2-rfx7 complex

Structure:

Ankyrin repeat family a protein 2. Chain: a. Fragment: unp residues 142-313. Synonym: rfxank-like protein 2. Engineered: yes. DNA-binding protein rfx7. Chain: x. Fragment: unp residues 85-101. Synonym: regulatory factor x 7, regulatory factor x domain-containing

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: ankra2, ankra. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic peptide

Resolution:

2.03Å R-factor: 0.221 R-free: 0.269

Authors:

C.Xu,W.Tempel,A.Dong,F.Mackenzie,C.Bountra,C.H.Arrowsmith, A.M.Edwards,J.Min,Structural Genomics Consortium (Sgc)

Key ref:

J.Nie et al. (2015). Ankyrin repeats of ANKRA2 recognize a PxLPxL motif on the 3M syndrome protein CCDC8. Structure, 23, 700-712. PubMed id: 25752541 DOI: 10.1016/j.str.2015.02.001

Date:

27-Jun-14 Release date: 03-Sep-14

Protein chain

Q9H9E1  (ANRA2_HUMAN) -  Ankyrin repeat family A protein 2 from Homo sapiens

Seq: 313 a.a.

Struc: 176 a.a.*

Protein chain

Q2KHR2  (RFX7_HUMAN) -  DNA-binding protein RFX7 from Homo sapiens

Seq: 1460 a.a.

Struc: 16 a.a.

* PDB and UniProt seqs differ at 5 residue positions (black crosses)

DOI no: 10.1016/j.str.2015.02.001

Structure 23:700-712 (2015)

PubMed id: 25752541

Ankyrin repeats of ANKRA2 recognize a PxLPxL motif on the 3M syndrome protein CCDC8.

J.Nie, C.Xu, J.Jin, J.A.Aka, W.Tempel, V.Nguyen, L.You, R.Weist, J.Min, T.Pawson, X.J.Yang.

ABSTRACT

No abstract given.