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PDBsum entry 4qox
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PDB id:
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Transferase
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Title:
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Crystal structure of cdpk4 from plasmodium falciparum, pf3d7_0717500
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Structure:
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Calcium-dependent protein kinase 4. Chain: a. Engineered: yes
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Source:
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Plasmodium falciparum. Organism_taxid: 36329. Gene: cdpk4, cpk4, pf07_0072. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9sf9.
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Resolution:
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2.75Å
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R-factor:
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0.206
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R-free:
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0.266
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Authors:
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A.K.Wernimont,J.R.Walker,A.Hutchinson,A.Seitova,H.He,P.Loppnau, M.Neculai,M.Amani,Y.H.Lin,M.Ravichandran,C.H.Arrowsmith,A.M.Edwards, C.Bountra,R.Hui,D.V.Lovato,Structural Genomics Consortium (Sgc)
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Key ref:
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A.K.Wernimont
et al.
Crystal structure of cdpk4 from plasmodium falciparum pf3d7_0717500.
To be published,
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Date:
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20-Jun-14
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Release date:
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03-Sep-14
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PROCHECK
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Headers
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References
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Q8IBS5
(CDPK4_PLAF7) -
Calcium-dependent protein kinase 4 from Plasmodium falciparum (isolate 3D7)
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Seq:
Struc:
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528 a.a.
462 a.a.
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Key: |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.2.7.11.1
- non-specific serine/threonine protein kinase.
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Reaction:
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1.
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L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H+
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2.
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L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H+
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L-seryl-[protein]
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+
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ATP
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=
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O-phospho-L-seryl-[protein]
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+
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ADP
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+
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H(+)
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L-threonyl-[protein]
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+
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ATP
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=
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O-phospho-L-threonyl-[protein]
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+
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ADP
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+
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H(+)
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
