PDBsum entry 4qeg

Structural protein

PDB id

4qeg

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Contents

			Protein chain

					89 a.a.

			Metals

					_CA ×3

			Waters ×121

PDB id:

4qeg

Links

Name:

Structural protein

Title:

Crystal structure of domain i10 from titin (space group p41)

Structure:

Titin. Chain: a. Fragment: domain i10. Synonym: connectin, rhabdomyosarcoma antigen mu-rms-40.14. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: ttn. Expressed in: escherichia coli. Expression_system_taxid: 511693.

Resolution:

2.00Å

R-factor:

0.188

R-free:

0.231

Authors:

J.Bogomolovas,S.Labeit,O.Mayans

Key ref:

J.Bogomolovas et al. Crystal structure of domain i10 from titin (space gro. To be published, .

Date:

16-May-14

Release date:

22-Jul-15

PROCHECK

	Headers

	References

Protein chain

Q8WZ42 (TITIN_HUMAN) - Titin from Homo sapiens

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Seq: Struc:					34350 a.a. 89 a.a.*

Key:

PfamA domain

Secondary structure

CATH domain

* PDB and UniProt seqs differ at 1 residue position (black cross)



		Enzyme reactions

Enzyme class:

E.C.2.7.11.1 - non-specific serine/threonine protein kinase.

[IntEnz] [ExPASy] [KEGG] [BRENDA]

Reaction:

1.	L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H⁺
2.	L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H⁺

L-seryl-[protein]	+	ATP	=	O-phospho-L-seryl-[protein]	+	ADP	+	H(+)

L-threonyl-[protein]	+	ATP	=	O-phospho-L-threonyl-[protein]	+	ADP	+	H(+)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site