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UniProt functional annotation for O08603 | ||
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| UniProt code: O08603. |
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| Organism: | |
Mus musculus (Mouse). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus. |
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| Function: | |
Acts as a ligand for KLRK1. {ECO:0000269|PubMed:10894171, ECO:0000269|PubMed:11248803, ECO:0000269|PubMed:11557981}. |
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| Subcellular location: | |
Cell membrane {ECO:0000269|PubMed:10894171, ECO:0000269|PubMed:8982867}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:10894171, ECO:0000269|PubMed:8982867}. |
| Tissue specificity: | |
Expressed predominantly in embryonic brain. {ECO:0000269|PubMed:8982867}. |
| Developmental stage: | |
Expressed predominantly during early embryogenesis. Detected at high levels in 7, 11 and 14-day-old embryos but not in 18-day-old embryos. Very low levels detected in adults. {ECO:0000269|PubMed:10894171, ECO:0000269|PubMed:8882725}. |
| Induction: | |
By retinoic acid. {ECO:0000269|PubMed:8882725}. |
| Ptm: | |
Glycosylated. {ECO:0000269|PubMed:8982867}. |
| Similarity: | |
Belongs to the NKG2D ligand family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.