PDBsum entry 4pby

Cell cycle

PDB id: 4pby

Contents

Protein chains

384 a.a.

12 a.a.

13 a.a.

Ligands

IPA

Waters ×251

PDB id:

4pby

Name:

Cell cycle

Title:

Structure of the human rbap48-mta1(656-686) complex

Structure:

Histone-binding protein rbbp4. Chain: a, b. Synonym: chromatin assembly factor 1 subunit c,caf-1 subunit c, chromatin assembly factor i p48 subunit,caf-i p48,nucleosome- remodeling factor subunit rbap48,retinoblastoma-binding protein 4, rbbp-4,retinoblastoma-binding protein p48. Engineered: yes. Metastasis-associated protein mta1. Chain: c, d.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: rbbp4, rbap48. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9. Synthetic: yes. Organism_taxid: 9606

Resolution:

2.50Å R-factor: 0.181 R-free: 0.225

Authors:

A.Murthy,S.Lejon,S.S.M.Alqarni,A.P.G.Silva,A.A.Watson,J.P.Mackay, E.D.Laue

Key ref:

S.S.Alqarni et al. (2014). Insight into the architecture of the NuRD complex: structure of the RbAp48-MTA1 subcomplex. J Biol Chem, 289, 21844-21855. PubMed id: 24920672 DOI: 10.1074/jbc.M114.558940

Date:

14-Apr-14 Release date: 11-Jun-14

Protein chains

Q09028  (RBBP4_HUMAN) -  Histone-binding protein RBBP4 from Homo sapiens

Seq: 425 a.a.

Struc: 384 a.a.

Protein chain

Q13330  (MTA1_HUMAN) -  Metastasis-associated protein MTA1 from Homo sapiens

Seq: 715 a.a.

Struc: 12 a.a.

Protein chain

Q13330  (MTA1_HUMAN) -  Metastasis-associated protein MTA1 from Homo sapiens

Seq: 715 a.a.

Struc: 13 a.a.

Enzyme reactions

• Enzyme class: Chains A, B, C, D: E.C.?

DOI no: 10.1074/jbc.M114.558940

J Biol Chem 289:21844-21855 (2014)

PubMed id: 24920672

Insight into the architecture of the NuRD complex: structure of the RbAp48-MTA1 subcomplex.

S.S.Alqarni, A.Murthy, W.Zhang, M.R.Przewloka, A.P.Silva, A.A.Watson, S.Lejon, X.Y.Pei, A.H.Smits, S.L.Kloet, H.Wang, N.E.Shepherd, P.H.Stokes, G.A.Blobel, M.Vermeulen, D.M.Glover, J.P.Mackay, E.D.Laue.

ABSTRACT

No abstract given.