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UniProt functional annotation for Q887Q3 | ||
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| UniProt code: Q887Q3. |
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| Organism: | |
Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000). |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas. |
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| Function: | |
Catalyzes the epimerization of beta-D-mannuronate to alpha-L- guluronate during the synthesis of the linear polysaccharide alginate (PubMed:24398681). In addition, is part of a periplasmic protein complex that protects alginate from degradation by AlgL by channeling the newly formed alginate polymer through a scaffold that transfers the alginate polymer through the periplasmic space to the outer membrane secretin AlgE (By similarity). {ECO:0000250|UniProtKB:Q51371, ECO:0000269|PubMed:24398681}. |
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| Catalytic activity: | |
Reaction=[(1->4)-beta-D-mannuronosyl](n) = [alginate](n); Xref=Rhea:RHEA:45572, Rhea:RHEA-COMP:11264, Rhea:RHEA-COMP:11270, ChEBI:CHEBI:58187, ChEBI:CHEBI:85311; EC=5.1.3.37; Evidence={ECO:0000269|PubMed:24398681}; |
| Pathway: | |
Glycan biosynthesis; alginate biosynthesis. {ECO:0000250|UniProtKB:Q51371}. |
| Subcellular location: | |
Periplasm {ECO:0000250|UniProtKB:Q51371}. |
| Domain: | |
The C-terminal region contains a right-handed beta-helix (RHbetaH) fold, which is common among proteins that bind and cleave long-chain linear polysaccharides. {ECO:0000269|PubMed:24398681}. |
| Similarity: | |
Belongs to the D-mannuronate C5-epimerase family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.