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UniProt functional annotation for Q9UMF0 | ||
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| UniProt code: Q9UMF0. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). |
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| Subcellular location: | |
Membrane; Single-pass type I membrane protein. |
| Tissue specificity: | |
Expressed on neurons in the most rostral segment of the mammalian brain, the telencephalon. |
| Ptm: | |
Glycosylation at Asn-54 is critical for functional folding. {ECO:0000250}. |
| Similarity: | |
Belongs to the immunoglobulin superfamily. ICAM family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.