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UniProt functional annotation for Q86W24 | ||
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| UniProt code: Q86W24. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
May be involved in inflammation and spermatogenesis. |
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| Subcellular location: | |
Cytoplasm {ECO:0000250|UniProtKB:Q6B966}. |
| Tissue specificity: | |
Testis-specific. {ECO:0000269|PubMed:16931801}. |
| Developmental stage: | |
In the testis, expressed mainly in A dark spermatogonia, mid and late spermatocytes and spermatids but not in mitotically active A pale and B spermatogonia. {ECO:0000269|PubMed:16931801}. |
| Domain: | |
Upon heterologous expression, a small proportion of the isolated Pyrin domain forms homodimers and higher oligomers. {ECO:0000269|PubMed:25004977}. |
| Similarity: | |
Belongs to the NLRP family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.