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UniProt functional annotation for P36941 | ||
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| UniProt code: P36941. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs. {ECO:0000269|PubMed:10799510, ECO:0000269|PubMed:8171323}. |
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| Subunit: | |
Self-associates. Associates with TRAF3, TRAF4 and TRAF5. {ECO:0000269|PubMed:8663299, ECO:0000269|PubMed:9511754, ECO:0000269|PubMed:9626059}. |
| Subunit: | |
(Microbial infection) Interacts with HCV core protein. {ECO:0000269|PubMed:8995654}. |
| Subcellular location: | |
Membrane; Single-pass type I membrane protein. |
Annotations taken from UniProtKB at the EBI.