PDBsum entry 4muv

Nucleotide binding protein

PDB id: 4muv

Contents

Protein chains

142 a.a.

Ligands

PCG ×2

Metals

_NA ×2

Waters ×356

PDB id:

4muv

Name:

Nucleotide binding protein

Title:

M. Loti cyclic-nucleotide binding domain mutant displaying inverted ligand selectivity, cyclic-gmp bound

Structure:

Cyclic nucleotide-gated potassium channel mll3241. Chain: a, b. Fragment: cyclic nucleotide binding domain, unp residues 216-355. Synonym: mlotik1 channel. Engineered: yes. Mutation: yes

Source:

Mesorhizobium loti. Organism_taxid: 266835. Strain: maff303099. Gene: mll3241. Expressed in: escherichia coli. Expression_system_taxid: 469008.

Resolution:

1.25Å R-factor: 0.138 R-free: 0.172

Authors:

F.Fonseca,J.Pessoa,J.H.Morais-Cabral

Key ref:

J.Pessoa et al. (2014). Determinants of ligand selectivity in a cyclic nucleotide-regulated potassium channel. J Gen Physiol, 144, 41-54. PubMed id: 24981229 DOI: 10.1085/jgp.201311145

Date:

23-Sep-13 Release date: 25-Jun-14

Protein chains

Q98GN8  (CNGK1_RHILO) -  Cyclic nucleotide-gated potassium channel mll3241 from Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099)

Seq: 355 a.a.

Struc: 142 a.a.*

* PDB and UniProt seqs differ at 5 residue positions (black crosses)

DOI no: 10.1085/jgp.201311145

J Gen Physiol 144:41-54 (2014)

PubMed id: 24981229

Determinants of ligand selectivity in a cyclic nucleotide-regulated potassium channel.

J.Pessoa, F.Fonseca, S.Furini, J.H.Morais-Cabral.

ABSTRACT

No abstract given.