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PDBsum entry 4mth
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Antimicrobial protein
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PDB id
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4mth
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PDB id:
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| Name: |
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Antimicrobial protein
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Title:
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Crystal structure of mature human regiiialpha
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Structure:
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Regenerating islet-derived protein 3-alpha 15 kda form. Chain: a. Synonym: reg-3-alpha, hepatointestinal pancreatic protein, hip/pap, human proislet peptide, pancreatitis-associated protein 1, regenerating islet-derived protein iii-alpha, reg iii-alpha. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: hip, pap, pap1, reg3a. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Resolution:
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1.47Å
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R-factor:
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0.187
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R-free:
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0.210
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Authors:
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M.G.Derebe
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Key ref:
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S.Mukherjee
et al.
(2014).
Antibacterial membrane attack by a pore-forming intestinal C-type lectin.
Nature,
505,
103-107.
PubMed id:
DOI:
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Date:
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19-Sep-13
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Release date:
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27-Nov-13
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PROCHECK
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Headers
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References
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Q06141
(REG3A_HUMAN) -
Regenerating islet-derived protein 3-alpha from Homo sapiens
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Seq:
Struc:
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175 a.a.
139 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 1 residue position (black
cross)
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DOI no:
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Nature
505:103-107
(2014)
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PubMed id:
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Antibacterial membrane attack by a pore-forming intestinal C-type lectin.
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S.Mukherjee,
H.Zheng,
M.G.Derebe,
K.M.Callenberg,
C.L.Partch,
D.Rollins,
D.C.Propheter,
J.Rizo,
M.Grabe,
Q.X.Jiang,
L.V.Hooper.
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ABSTRACT
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Links
