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UniProt functional annotation for Q2G506 | ||
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| UniProt code: Q2G506. |
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| Organism: | |
Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CCUG 56034 / CIP 105152 / NBRC 16084 / F199). |
| Taxonomy: | |
Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales; Sphingomonadaceae; Novosphingobium. |
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| Function: | |
Mediates the ATP-dependent export of glutathione-conjugated substrates, such as heavy metal-glutathione conjugates. ATP hydrolysis is stimulated by glutathione binding. Protects cells against toxic heavy metal ions, such as silver and mercury ions. May also mediate the transport of glutathione-conjugated aromatic hydrocarbons, such as dinitrobenzene. {ECO:0000269|PubMed:24604198}. |
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| Subunit: | |
Homodimer. {ECO:0000269|PubMed:24604198}. |
| Subcellular location: | |
Cell inner membrane {ECO:0000269|PubMed:24604198}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:24604198}. |
| Similarity: | |
Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.