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PDBsum entry 4m9e
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Transcription/DNA
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PDB id
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4m9e
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PDB id:
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| Name: |
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Transcription/DNA
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Title:
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Structure of klf4 zinc finger DNA binding domain in complex with methylated DNA
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Structure:
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Krueppel-like factor 4. Chain: a. Fragment: unp residues 396-483. Synonym: epithelial zinc finger protein ezf, gut-enriched krueppel- like factor. Engineered: yes. DNA (5'-d( Gp Ap Gp Gp (5Cm)p Gp Tp Gp Gp C)-3'). Chain: b. Engineered: yes.
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Source:
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Mus musculus. Mouse. Organism_taxid: 10090. Gene: klf4, ezf, gklf, zie. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: DNA synthesis. Other_details: DNA synthesis
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Resolution:
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1.85Å
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R-factor:
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0.189
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R-free:
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0.234
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Authors:
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Y.Liu,Y.O.Olanrewaju,R.M.Blumenthal,X.Zhang,X.Cheng
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Key ref:
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Y.Liu
et al.
(2014).
Structural basis for Klf4 recognition of methylated DNA.
Nucleic Acids Res,
42,
4859-4867.
PubMed id:
DOI:
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Date:
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14-Aug-13
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Release date:
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12-Feb-14
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PROCHECK
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Headers
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References
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Q60793
(KLF4_MOUSE) -
Krueppel-like factor 4 from Mus musculus
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Seq:
Struc:
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483 a.a.
85 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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G-A-G-G-5CM-G-T-G-G-C
10 bases
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G-C-C-A-5CM-G-C-C-T-C
10 bases
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DOI no:
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Nucleic Acids Res
42:4859-4867
(2014)
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PubMed id:
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Structural basis for Klf4 recognition of methylated DNA.
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Y.Liu,
Y.O.Olanrewaju,
Y.Zheng,
H.Hashimoto,
R.M.Blumenthal,
X.Zhang,
X.Cheng.
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ABSTRACT
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Links
