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PDBsum entry 4m84
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Transferase/transferase inhibitor
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PDB id
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4m84
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References listed in PDB file
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Key reference
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Title
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Potent and selective inhibitors of cdpk1 from t. Gondii and c. Parvum based on a 5-Aminopyrazole-4-Carboxamide scaffold.
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Authors
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Z.Zhang,
K.K.Ojo,
R.Vidadala,
W.Huang,
J.A.Geiger,
S.Scheele,
R.Choi,
M.C.Reid,
K.R.Keyloun,
K.Rivas,
L.K.Siddaramaiah,
K.M.Comess,
K.P.Robinson,
P.J.Merta,
L.Kifle,
W.G.Hol,
M.Parsons,
E.A.Merritt,
D.J.Maly,
C.L.Verlinde,
W.C.Van voorhis,
E.Fan.
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Ref.
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Acs Med Chem Lett, 2014,
5,
40-44.
[DOI no: ]
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PubMed id
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Abstract
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No abstract given.
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Secondary reference #1
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Title
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Toxoplasma gondii calcium-Dependent protein kinase 1 is a target for selective kinase inhibitors.
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Authors
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K.K.Ojo,
E.T.Larson,
K.R.Keyloun,
L.J.Castaneda,
A.E.Derocher,
K.K.Inampudi,
J.E.Kim,
T.L.Arakaki,
R.C.Murphy,
L.Zhang,
A.J.Napuli,
D.J.Maly,
C.L.Verlinde,
F.S.Buckner,
M.Parsons,
W.G.Hol,
E.A.Merritt,
W.C.Van voorhis.
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Ref.
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Nat Struct Biol, 2010,
17,
602-607.
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PubMed id
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Secondary reference #2
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Title
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Multiple determinants for selective inhibition of apicomplexan calcium-Dependent protein kinase cdpk1.
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Authors
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E.T.Larson,
K.K.Ojo,
R.C.Murphy,
S.M.Johnson,
Z.Zhang,
J.E.Kim,
D.J.Leibly,
A.M.Fox,
M.C.Reid,
E.J.Dale,
B.G.Perera,
J.Kim,
S.N.Hewitt,
W.G.Hol,
C.L.Verlinde,
E.Fan,
W.C.Van voorhis,
D.J.Maly,
E.A.Merritt.
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Ref.
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J Med Chem, 2012,
55,
2803-2810.
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PubMed id
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