PDBsum entry 4lp5

Signaling protein

PDB id: 4lp5

Contents

Protein chains

211 a.a.

302 a.a.

PDB id:

4lp5

Name:

Signaling protein

Title:

Crystal structure of the full-length human rage extracellular domain (vc1c2 fragment)

Structure:

Advanced glycosylation end product-specific receptor. Chain: b, a. Fragment: v, c1 and c2 domains (vc1c2 fragment), full-length ectodomain (unp residues 23-323). Synonym: receptor for advanced glycosylation end products. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: ager, rage. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

3.80Å R-factor: 0.247 R-free: 0.286

Authors:

L.Yatime,G.R.Andersen

Key ref:

L.Yatime and G.R.Andersen (2013). Structural insights into the oligomerization mode of the human receptor for advanced glycation end-products. Febs J, 280, 6556-6568. PubMed id: 24119142 DOI: 10.1111/febs.12556

Date:

15-Jul-13 Release date: 16-Oct-13

Protein chain

Q15109  (RAGE_HUMAN) -  Advanced glycosylation end product-specific receptor from Homo sapiens

Seq: 404 a.a.

Struc: 211 a.a.

Protein chain

Q15109  (RAGE_HUMAN) -  Advanced glycosylation end product-specific receptor from Homo sapiens

Seq: 404 a.a.

Struc: 302 a.a.*

* PDB and UniProt seqs differ at 3 residue positions (black crosses)

DOI no: 10.1111/febs.12556

Febs J 280:6556-6568 (2013)

PubMed id: 24119142

Structural insights into the oligomerization mode of the human receptor for advanced glycation end-products.

L.Yatime, G.R.Andersen.

ABSTRACT

No abstract given.